MODIFICATION OF RNA, PRODUCING AN INCREASED TRANSCRIPT STABILITY AND TRANSLATION EFFICIENCY
摘要
The invention relates to the stabilisation of RNA, in particular mRNA and to the increased translation of mRNA. The invention specifically relates to three modifications of RNA, in particular in vitro transcribed RNA, which produce an increased transcript stability and translation efficiency.
申请公布号
WO2007036366(A2)
申请公布日期
2007.04.05
申请号
WO2006EP09448
申请日期
2006.09.28
申请人
JOHANNES GUTENBERG-UNIVERSITAET MAINZ, VERTRETEN DURCH DEN PRAESIDENTEN;SAHIN, UGUR;HOLTKAMP, SILKE;TUERECI, OEZLEM;KREITER, SEBASTIAN
发明人
SAHIN, UGUR;HOLTKAMP, SILKE;TUERECI, OEZLEM;KREITER, SEBASTIAN