| 摘要 |
A method of administering to the eye a liquid ophthalmic formulation, comprising an ophthalmologically acceptable liquid and optionally containing an ophthalmologically-active substance, characterized in that the formulatio n has a viscosity in the range 10-3 to 1.0 Pa.s and a resistivity lower than 1 04 ohm.cm, and that a jet of the formulation is ejected towards the eye, from a spray nozzle (12) situated adjacent to a piezoelectric or electromagnetic transducer (7), to form a stream of uniformly-sized, equally spaced, uncharg ed droplets, the stream of uncharged droplets is subsequently directed past a charging electrode (13) to induce an electric charge on each droplet in the stream, and the charged droplets discharge their electric charge by earthing on contact with the eye; and spraying apparatus suitable for use in that method.
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