发明名称 |
Impiantable polymeric device for sustained release of nalmefene |
摘要 |
The present invention provides compositions, methods, and kits for administration of nalmefene for treatment of alcoholism, nicotine dependence, or another condition for which treatment with nalmefene is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases nalmefene continuously with generally linear release kinetics for extended periods of time. Nalmefene is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with nalmefene. |
申请公布号 |
ZA200509063(B) |
申请公布日期 |
2007.03.28 |
申请号 |
ZA20050009063 |
申请日期 |
2004.05.27 |
申请人 |
TITAN PHARMACEUTICALS, INC. |
发明人 |
PATEL, RAJESH A.;BUCALO, LOUIS R.;COSTANTINI, LAUREN |
分类号 |
A61K;A61K9/00;A61K9/20;A61K9/26;A61K9/32;A61K31/485;A61P;A61P25/32;A61P25/34 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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