发明名称 |
Humanized antibodies that sequester abeta peptide |
摘要 |
A method to treat conditions characterized by formation of amyloid plaques both prophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble Abeta peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide Abeta. |
申请公布号 |
US7195761(B2) |
申请公布日期 |
2007.03.27 |
申请号 |
US20020226435 |
申请日期 |
2002.08.21 |
申请人 |
WASHINGTON UNIVERSITY |
发明人 |
HOLTZMAN DAVID M.;DEMATTOS RONALD;BALES KELLY R.;PAUL STEVEN M.;TSURUSHITA NAOYA;VASQUEZ MAXIMILIANO |
分类号 |
C07K16/18;C12N15/09;A61K;A61K39/00;A61K39/395;A61P;A61P25/28;C07K;C12N;C12N5/10;C12N15/13;C12R1/91 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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