发明名称 |
ОБЛАДАЮЩИЕ ПРОТИВООПУХОЛЕВЫМ ДЕЙСТВИЕМ 2-ЗАМЕЩЕННЫЕ D-ГОМОЭСТРА-1, 3, 5( 10 )-ТРИЕН-3-ИЛСУЛЬФАМАТЫ |
摘要 |
This invention relates to 2-substituted D-homo-estra-1,3,5(10)-trien-3-yl sulfamates of general formula I (I), in which R3 means a C1-C5-alkyl or C1-C5-alkyloxy group as well as their use for the production of a pharmaceutical agent for treating tumor diseases, which can be influenced positively by the inhibition of tubulin polymerization. The compounds according to the invention are distinguished by a D-homo-substitution. They have a special action with respect to tubulin polymerization inhibition and can be used, for example, for treating prostate cancer |
申请公布号 |
RU2005128830(A) |
申请公布日期 |
2007.03.27 |
申请号 |
RU20050128830 |
申请日期 |
2004.02.19 |
申请人 |
ШЕРИНГ АКЦИЕНГЕЗЕЛЬШАФТ (DE) |
发明人 |
ХИЛЛИШ Александер (DE);ПЕТЕРС Олаф (DE);ГЕГЕ Кристиан (DE);ЗИМАЙСТЕР Герхард (DE);УНГЕР Эберхард (DE) |
分类号 |
C07J63/00;A61K31/565;A61P35/00;C07J31/00;C07J41/00 |
主分类号 |
C07J63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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