发明名称 Method for preparing 6-aminomethyl-6, 11-dihydro-5h-dibenz[b,e]azepine
摘要 A production method of 6-aminomethyl-6,11-dihydro-5H-dibenz[b,e]azepin characterized in that said compound is produced via N-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-o-hydroxymethylbenzamide which is prepared by reducing 2-(11H-dibenz[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione employing a metal hydride or a metal hydride complex in a water based alcohol, and N-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-o-hydroxymethylbenzamide which is useful for the aforesaid production method.
申请公布号 US7196193(B2) 申请公布日期 2007.03.27
申请号 US20040510008 申请日期 2004.09.30
申请人 KONICA MINOLTA CHEMICAL CO., LTD. 发明人 IKEDA SHIN;TAKAHASHI YASUHIRO
分类号 C07D223/20;A61K31/55;C07D223/18;C07D403/06 主分类号 C07D223/20
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