Ester derivatives

摘要

This invention relates to compounds which exhibit selective muscarinic M₃ receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); [in which A signifies a group expressed by a formula (a₀) or (b₀); Ar signifies optionally substituted aryl or heteroaryl; B¹ and B² signify aliphatic hydrocarbon; R¹ signifies fluorine-substituted cycloalkyl; R², R³ and R⁴ signify lower alkyl, single bond or alkylene bonded to B¹, or R² and R³ are united to signify alkylene; R⁵ and R⁷ signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B²; R⁶ signifies hydrogen, lower alkyl or a group expressed as -N(R⁸)R⁹; and X^- signifies an anion].