DERIVATIZATION REAGENT FOR SOFT IONIZATION PROCESS

摘要

Disclosed is a means for enhancing the detection sensitivity in mass spectrometry using a soft ionization process of a phenol compound and an amine compound. Specifically disclosed is a derivatization reagent for a phenol compound or an amine compound, which contains a compound represented by the formula (I) below or a quaternarized product thereof. (I) (In the formula, X represents a halogen; Y<SUB>1</SUB> and Y<SUB>2</SUB> represent nitro groups or the like; A represents an N or the like; Q represents a C<SUB>1</SUB>-C<SUB>4</SUB> alkylene group; and R<SUB>1</SUB>, R<SUB>2</SUB> and R<SUB>3</SUB> satisfy, for example, the following condition (a). (a) R<SUB>1</SUB> and R<SUB>2</SUB> independently represent a C<SUB>1</SUB>-C<SUB>4</SUB> alkyl group, and R<SUB>3</SUB> represents a hydrogen or a C<SUB>1</SUB>-C<SUB>4</SUB> alkyl group.)