PRODRUGS OF T3 AND T4 WITH ENHANCED BIOAVAILABILITY
摘要
The invention relates to compositions of amino acid and peptide conjugates comprising T3 and/or T4. The T3 or T4 is covalently attached to at least one amino acid via the N-terminus, the C-terminus, a side chain of the peptide carrier, and/or interspersed within the peptide chain. Also discussed are methods for protecting and administering active agents and methods for treating thyroid disorders.
申请公布号
WO2007030577(A2)
申请公布日期
2007.03.15
申请号
WO2006US34790
申请日期
2006.09.08
申请人
NEW RIVER PHARMACEUTICALS INC.;MONCRIEF, JAMES SCOTT;MICKLE, TRAVIS;OLON, LAWRENCE;PICCARIELLO, THOMAS
发明人
MONCRIEF, JAMES SCOTT;MICKLE, TRAVIS;OLON, LAWRENCE;PICCARIELLO, THOMAS