PHARMACEUTICAL COMPOSITIONS CONTAINING POLYUNSATURATED FATTY ACID AND AT LEAST ONE OF AN IMMUNOSUPPRESSIVE AGENT OR AN ANTINEOPLASTIC AGENT

摘要

Polyunsaturated fatty acid ("PUFA") or a pharmacologically acceptable salt or derivative thereof (such as EPA and/or DHA) is used in combination with at least one of an immunosuppressive agent or an antineoplastic agent or a pharmacologically acceptable salt or derivative thereof in the treatment of conditions involving acutely or chronically inadequate immune response by topical application of said active agents to at least a portion of the intestinal mucosa. Specific conditions that may be treated include chronic inflammatory disease (e.g. Chrohn's disease and ulcerative colitis) and tumour disease (e.g. bowel cancer and prostate cancer). One advantage of preferred embodiments of the invention is that bioavailability of immunosuppressive or antineoplastic agents is increased. ® KIPO & WIPO 2007