发明名称 |
Snail, a new marker for tumour invasion and target protein of new antitumoral compounds |
摘要 |
The Snail transcription factor has been identified as a repressor of the expression of E-cadherin. The expression of Snail induces invasive and metastatic capacity in tumour cells. This invention presents: a new target protein, Snail, for the identification of new antitumoral compounds and a new diagnostic tumour marker, indicative of tissue invasion and metastatic capacity.
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申请公布号 |
US2007054307(A1) |
申请公布日期 |
2007.03.08 |
申请号 |
US20060591825 |
申请日期 |
2006.11.02 |
申请人 |
CANO GARCIA AMPARO;NIETO TOLEDANO MA ANGELA;RODRIGO CASTRO MA ISABEL;LOCASCIO ANNAMARIA;GARCIA DEL BARRIO MARTA;FERNANDEZ DE VALDERRAMA MARIA;PORTILLO PEREZ FRANCISCO;PEREZ MARENO MIRNA A |
发明人 |
CANO GARCIA AMPARO;NIETO TOLEDANO MA ANGELA;RODRIGO CASTRO MA ISABEL;LOCASCIO ANNAMARIA;GARCIA DEL BARRIO MARTA;FERNANDEZ DE VALDERRAMA MARIA JOSE B.;PORTILLO PEREZ FRANCISCO;PEREZ MARENO MIRNA A. |
分类号 |
C12Q1/68;A61K38/00;A61K48/00;C07K14/47;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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