发明名称 |
p53 and VEGF regulate tumor growth of NOS2 expressing cancer cells |
摘要 |
The invention provides, for example, in vitro and in vivo methods for screening modulators of NOS-2 activity using p53 mutant cells, methods of predicting the benefit of administering NOS-2 inhibitors to a cancer patient, and methods of treating cancer by administering NOS-2 inhibitors to patients with p53 mutant cancers.
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申请公布号 |
US2007056049(A1) |
申请公布日期 |
2007.03.08 |
申请号 |
US20050195006 |
申请日期 |
2005.08.01 |
申请人 |
THE GOVT. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES |
发明人 |
AMBS STEFAN;HARRIS CURTIS |
分类号 |
A61K49/00;A61K31/195;A61K31/198;G01N33/50;G01N33/53 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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