摘要 |
A compound having a general formula (II) wherein R<SUB>1 </SUB>is saturated or unsaturated alkyl, amino-alcohol, diamino, cycloalkyl, and C(-O)(CH<SUB>2</SUB>)<SUB>n</SUB>NR'R'', (CH<SUB>2</SUB>)<SUB>n</SUB>CHOHCH<SUB>2</SUB>NR'R'', wherein n is an integer, R<SUB>Q, R</SUB><SUB>T</SUB>, R', and R'' are each independently a hydrogen, halogen, hydroxyl, saturated, unsaturated, aliphatic, or branched alkyl, substituted or unsubstituted (CH<SUB>2</SUB>)<SUB>m</SUB>-(hetero)aryl, and sulfonylamide; q and r are each an integer independently selected from 1-4; and pharmaceutically acceptable salts thereof, and the new therapeutic uses thereof and similar compounds as defibrillating, and/or anti-fibrillatory, and/or anti-arrhythmic and/or anti-ischemic drugs. |