| 摘要 |
<p>Methods for obtaining the substituted pyrazoline compounds of general formula (Ia) as well as the intermediates of general formula (III) to this compound. Thus 5-(R 10 ,R 11 ,R 12 -phenyl)-1-(R 13 ,R 14 ,R 15 -phenyl)-N-(piperidin-1-yl)-4,5-dihydro-1H-pyrazole-3-carboxamide (II) can be obtained by the reaction of an activated carbonyl compound derived from 5-(R 10 ,R 11 ,R 12 -phenyl)-1-(R 13 ,R 14 ,R 15 -phenyl)-N-(piperidin-1-yl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid (IIIa) with N-aminopiperidine in the presence or absence of an acid acceptor or suitable condensing agent.</p> |
