发明名称 |
Modulator of TNF/NGF superfamily receptors and soluble oligomeric TNF/NGF superfamily receptors |
摘要 |
The present invention generally concerns novel proteins which bind to the intracellular domains of the p55 and p75 TNF-Rs and the FAS-R, which are capable of modulating the function of the p55 and p75 TNF-Rs and the FAS-R, and the DNA sequences which encode them. The present invention also concerns new soluble oligomeric TNF-Rs, oligomeric FAS-Rs and oligomeric receptors having a mixture of TNF-Rs and FAS-Rs. In addition, the present invention concerns methods of preparation and uses of all of the aforementioned.
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申请公布号 |
US7186682(B2) |
申请公布日期 |
2007.03.06 |
申请号 |
US20030349977 |
申请日期 |
2003.01.24 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
WALLACH DAVID;BOLDIN MARK;METT IGOR;VARFOLOMEEV EUGENE |
分类号 |
A01N37/18;A61K38/00;C07K14/47;C07K14/525;C07K14/705;C07K14/715 |
主分类号 |
A01N37/18 |
代理机构 |
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地址 |
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