| 发明名称 |
Polypeptide conjugates with extended circulating half-lives |
| 摘要 |
The present invention relates to compounds and methods for synthesizing compounds wherein the compounds exhibit extended circulating half-life in the blood. The increase in circulating half-life is achieved by conjugating polypeptides to binding groups that exhibit high affinity for human serum albumin.
|
| 申请公布号 |
US7186797(B2) |
申请公布日期 |
2007.03.06 |
| 申请号 |
US20040487025 |
申请日期 |
2004.07.15 |
| 申请人 |
EPIX PHARMACEUTICALS, INC. |
发明人 |
WEST THEODORE R.;MCMURRY THOMAS J;DUMAS STEPHANE;KOLODZIEJ ANDREW |
| 分类号 |
A61K38/00;C07K1/113;A61K38/28;A61K47/48;A61P5/50;C07F9/09;C07F9/553;C07F9/572;C07K1/107;C07K2/00;C07K14/435;C07K14/505;C07K14/525;C07K14/53;C07K14/535;C07K14/56;C07K14/565;C07K14/57;C07K14/61;C07K14/62;C07K14/64 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
