| 摘要 |
The present invention relates to the use of alpha (2) macroglobulin ("alpha2M") receptor as a heat shock protein receptor, cells that express the alpha2M receptor bound to an HSP, and antibodies and other molecules that bind the alpha2M receptor-HSP complex. The invention also relates to screening assays to identify compounds that modulate the interaction of an HSP with the alpha2M receptor, and methods for using compositions comprising alpha2M-receptor sequences for the diagnosis and treatment of immune disorders, proliferative disorders, and infectious diseases.
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