PLY-GBS MUTANT LYSINS

摘要

Methods, compositions and articles of manufacture useful for the treatment of various Group B streptococci (GBS) bacteria are provided. Various bacterial lysins, including certain PIyGBS mutant lysins, are provided. In particular, PIyGBS mutant lysins having lytic killing activity against Group B streptococci (GBS) bacteria are provided, including PIyGBS mutant lysins with greater killing activity against Group B streptococci (GBS) bacteria than the non- mutated PIyGBS bacterial lysin.