发明名称 |
EXTRACTS OF LATEX OF CALOTROPIS PROCERA AND TO A METHOD OF PREPARATION THEREOF |
摘要 |
<p>The invention relates to aqueous suspension of dried latex (DL) of Calotropis procera and to a method of preparation for the prevention/treatment of cancer. The DL suspension when administered orally in the X-myc mice-a transgenic mouse model of hepatocellular carcinoma (HCC), was effective in protecting the animals from the atypical mitosis and displastic/neoplastic changes occurring in vivo. Further, the DL suspension did not show any observable side effects when administered orally to the animals for 16 weeks. Further, the purified fractions of the latex were found to exhibit potent cytotoxic activity in in vitro cell culture system using two different cancer cell lines.</p> |
申请公布号 |
EP1755627(A1) |
申请公布日期 |
2007.02.28 |
申请号 |
EP20050735493 |
申请日期 |
2005.04.07 |
申请人 |
ALL INDIA INSTITUTE OF MEDICAL SCIENCES;INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY |
发明人 |
KUMAR, VIJAY L.;KUMAR, VIJAY |
分类号 |
A61K35/68;A61K36/27;A61K36/51;A61P35/00 |
主分类号 |
A61K35/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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