7-Aryl-3,9-diazabicyclo (3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases

摘要

3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) (wherein the variables are as defined in the specification) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions are disclosed. The disclosure also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.