DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS

摘要

The invention relates to compounds having general formula (I) wherein R represents: a hydrogen atom or a halogen atom; or a phenyl group which is optionally substituted by one or more halogen atoms, by one or more groups selected from groups (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy, nitro, amino, di(C<SUB>1</SUB>-C<SUB>3</SUB>)alkylamino, trifluoromethyl, trifluoromethoxy, cyano, hydroxy, acetyl or methylenedioxy; or a group selected from among pyridinyl, pyrazolyl, imidazolyl, triazolyl, tetrazolyl, oxazolyl, thiazolyl, oxadiazolyl, thiadiazolyl, thienyl, furyl, isoxazolyl, isothiazolyl, pyrrolyl, naphthyl, which can be optionally substituted by one or more groups selected from among halogen atoms, groups (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy, trifluoromethoxy, trifluoromethyl, nitro, cyano, hydroxy, amino, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkylamino or di(C<SUB>1</SUB>-C<SUB>6</SUB>)alkylamino; in the form of a base or an acid addition salt, as well as in the form of a hydrate or solvate. The invention also relates to the method of preparing said compounds and to the use thereof in therapeutics.