| 发明名称 |
SUBSTITUTED PIPERAZINES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS |
| 摘要 |
<p>The invention relates to compounds of formula I or pharmaceutically acceptable salts or solvates thereof: where Ar<SUB>1</SUB>, Ar<SUB>2</SUB>, H<SUB>y</SUB>, L, R<SUB>1</SUB>, m and n are as defined in the description. The invention also includes pharmaceutical compositions and uses thereof, processes for making the compounds, as well as methods for the medical treatment of mGluR5-mediated disorders.</p> |
| 申请公布号 |
WO2007021573(A1) |
申请公布日期 |
2007.02.22 |
| 申请号 |
WO2006US30392 |
申请日期 |
2006.08.04 |
| 申请人 |
ASTRAZENECA AB;NPS PHARMACEUTICALS, INC.;EDWARDS, LOUISE;SLASSI, ABDELMALIK;ISAAC, METHVIN;MCLEOD, DONALD |
发明人 |
EDWARDS, LOUISE;SLASSI, ABDELMALIK;ISAAC, METHVIN;MCLEOD, DONALD |
| 分类号 |
C07D401/12;A61K31/4545;A61K31/455;A61K31/497;A61K31/506;A61P1/00;A61P25/00;C07D403/12;C07D413/12 |
主分类号 |
C07D401/12 |
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