| 发明名称 |
INHIBITORS OF HISTONE DEACETYLASE. |
| 摘要 |
<p>The invention relates to a series of compounds useful for inhibiting histone deacetylase (HDAC) enzymatic activity. The invention also provides a method for inhibiting histone descetylase in a cell using said compounds as well as a method for treating cell proliferative diseases and conditions using said HDAC inhibitors. Further, the invention provides pharmaceutical compositions comprising the HDAC inhibiting compounds and a pharmaceutically acceptable carrier.</p> |
| 申请公布号 |
MXPA06010900(A) |
申请公布日期 |
2007.02.21 |
| 申请号 |
MX2006PA10900 |
申请日期 |
2005.03.29 |
| 申请人 |
METHYLGENE, INC. |
发明人 |
DANIEL DELORME;ARKADII VAISBURG;SILVANA LEIT;STEPHANE RAEPPEL;SYLVIE FRECHETTE;ZHIHONG ZHOU;OSCAR MORADEI;GILIANE BOUCHAIN;ISABELLE PAQUIN;FREDERIC GAUDETTE;LJUBOMIR ISAKOVIC |
| 分类号 |
C07D495/04;A61K31/343;A61K31/36;A61K31/40;A61K31/428;A61K31/4439;A61K31/455;A61K31/496;A61K31/505;A61K31/5377;C07C237/40;C07D209/08;C07D209/14;C07D209/16;C07D213/22;C07D213/38;C07D213/74;C07D231/38;C07D235/16;C07D237/20;C07D239/26;C07D239/42;C07D239/48;C07D263/58;C07D271/06;C07D277/68;C07D277/74;C07D277/82;C07D295/092;C07D295/135;C07D295/185;C07D307/85;C07D333/38;C07D401/04;C07D401/12;C07D403/04;C07D403/12;C07D409/04;C07D413/10;C07D413/12;C07D417/04;C07D417/12;C07D471/04 |
主分类号 |
C07D495/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
