发明名称 |
STABILIZED 3-HYDROXYFLAVAN COMPOSITIONS AND METHODS THEREFOR |
摘要 |
<p>Compositions and methods are directed to covalent adducts between reducing agents and optionally substituted 3-hydroxyflavans, wherein the reducing agent is covalently bound to the B-ring of the 3-hydroxyflavan. Such adducts exhibit markedly increased stability towards oxidation as compared to the unmodified 3-hydroxyflavan. Particularly preferred 3-hydroxyflavans include green tea catechins, and especially EGCG, while especially preferred reducing agents include NAC and glutathione.</p> |
申请公布号 |
WO2007018502(A1) |
申请公布日期 |
2007.02.15 |
申请号 |
WO2005US26521 |
申请日期 |
2005.07.26 |
申请人 |
JP;CA;JP;JP |
发明人 |
JOVANOVIC, SLOBODAN;HOJO, HIROSHI;HARA, YUKIHIKO |
分类号 |
A61K31/353;C07D311/62 |
主分类号 |
A61K31/353 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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