发明名称 DERIVATIVES OF N-[PHENYL(PIPERIDINE-2-YL)METHYL]BENZAMIDE, METHOD OF SYNTHESIS AND USE IN THERAPY
摘要 The invention relates to compounds having general formula (I), wherein - A denotes: a group with formula N-R| in which R1 denotes a hydrogen atom. an alkyl group, a phenylalkyl group, a phenylalkyl group, an alkenyl group or an alkynyl group; or a group with formula N+(O-)R1] in which R1 is as defined above; or a group with formula N+(R-)R1 in which R denotes an alkyl group and R1 is as defined above. X denotes a hydrogen atom or one or more subslituents selected from the halogen atoms and the trifluoromethyl, alkyl and alcoxy groups. - R2; denotes a hydrogen atom, one or more substituents selected from the halogen atoms and the trifluoromelhyl, alkyl, alkoxy, amino groups with formula NR3R4 in which R3 and R4 each denote a hydrogen atom or an alkyl group or, together with the nitrogen atom bearing same, form a pyrrolidine, piperidine or morpholine ring, or an optionally substituted phenyl group. The invention is suitable for use in therapeutics. (I)
申请公布号 UA78025(C2) 申请公布日期 2007.02.15
申请号 UA20041008110 申请日期 2003.04.17
申请人 SANOFI-AVENTIS 发明人
分类号 A61K31/445;A61K;A61K31/4458;A61K31/452;A61P;A61P1/00;A61P11/16;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P29/00;A61P43/00;C07D;C07D211/26;C07D211/32;C07D211/94 主分类号 A61K31/445
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