发明名称 |
SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES TECHNICAL FIELD OF THE INVENTION |
摘要 |
<p>The present invention relates to novel substituted 2-benzyloxy-benzoic acid amide derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menthol Receptor 1 (CMR-1) activity, in particular for the treatment of urological diseases or disorders, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor oeractivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, and inflammatory disorders such as asthma and chronic obstructive pulmonary (or airways) disease (COPD).</p> |
申请公布号 |
WO2007017093(A1) |
申请公布日期 |
2007.02.15 |
申请号 |
WO2006EP07298 |
申请日期 |
2006.07.25 |
申请人 |
BAYER HEALTHCARE AG;LAMPE, THOMAS;ALONSO-ALIJA, CRISTINA;BECK, HARTMUT;ROSENTRETER, ULRICH;SANDNER, PETER;STAHL, ELKE;STELTE-LUDWIG, BEATRIX |
发明人 |
LAMPE, THOMAS;ALONSO-ALIJA, CRISTINA;BECK, HARTMUT;ROSENTRETER, ULRICH;SANDNER, PETER;STAHL, ELKE;STELTE-LUDWIG, BEATRIX |
分类号 |
C07C235/60;A61K31/166;A61P13/00;C07C235/66;C07C271/20;C07C323/42;C07D231/16;C07D239/34;C07D307/81;C07D317/60;C07D317/62;C07D333/24 |
主分类号 |
C07C235/60 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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