| 摘要 |
PROBLEM TO BE SOLVED: To provide a transdermal administration device which increases a transfer speed of a medical substance into a skin and the transferring amount of the medical substance. SOLUTION: An action side structure body A1 is equipped with an electrode member 11 connected to the positive pole of a power source C, an electrolytic solution retaining part 12 which retains an electrolytic solution and makes contact with the electrode member 11, and a bipolar membrane 13 which is disposed on the front side (on the side of a skin) of the electrolytic solution retaining part 12 and comprises an anion exchange membrane 13A and a cation exchange membrane 13C, and is housed in a container 14. A non-action side structure body B is equipped with an electrode member 21 connected to the negative pole of the power source C and an electrolytic solution retaining part 22 which retains an electrolytic solution and makes contact with the electrode member 21, and is housed in a container 24. Consequently, H<SP>+</SP>ions generated by the electrolysis of water in the bipolar membrane 13 are supplied to the front side of the bipolar membrane 13 and are transferred in the skin S by the action of a positive voltage V1. Then a pH value of the skin S is reduced. Not only the molecules of the medical substance but also negative medical ions in a medical solution layer 15 are transferred in the skin S. COPYRIGHT: (C)2007,JPO&INPIT
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