| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for producing an extract of Macaranga tanarium, with which an extract of Macaranga tanarium containing a useful component derived from Macaranga tanarium in a high concentration is readily produced. <P>SOLUTION: The extract of Macaranga tanarium is produced by extracting Macaranga tanarium with water to give a solid component and then extracting the solid component with an organic solvent. Water at ≥90°C is preferably used in the water extraction. An extraction solvent comprising a lower alcohol as a main component is preferably used in the organic solvent extraction. The extract of Macaranga tanarium contains nymphaeol B and C, preferably contains nymphaeol A and/or propolin A besides nymphaeol B and C. The figure (a) shows chromatogram obtained by HPLC analysis of a water extracted solution by extraction of leaves of Macaranga tanarium with water, the figure (b) shows chromatogram obtained by HPLC analysis of a primary extract obtained by organic solvent extraction of the solid component with ethanol after the water extraction and the figure (c) shows chromatogram obtained by HPLC analysis of a secondary extract obtained by further organic solvent extraction of the primary extract with ethanol. <P>COPYRIGHT: (C)2007,JPO&INPIT |
