| 摘要 |
<p>Peptides derived from antibodies with reactivity against a glycosyl phosphatidyl inositol (GPI) linkage epitope may be used in the therapy and diagnosis of a variety of diseases, which are related to the inappropriate presence in the body of autoantibodies which are reactive with GPI linkage epitopes. The antibodies against the GPI linkage epitopes are preferably multi-specific, and may also have reactivity against anti-TCR V b antibody, phospholipids such as cardiolipin, and single or double strand DNA. The diseases which may be treated or diagnosed using these peptide include, in particular, diabetes, together with a wide range of autoimmune conditions, cancer and cardiovascular disease.</p> |
