| 发明名称 |
NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS |
| 摘要 |
<p>This invention relates to nicotinamide derivatives of general formula (I): in which R1, Z and R2 have the meanings defined herein, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of such derivatives.</p> |
| 申请公布号 |
EP1651640(B1) |
申请公布日期 |
2007.02.14 |
| 申请号 |
EP20040744026 |
申请日期 |
2004.07.13 |
| 申请人 |
PFIZER LIMITED;PFIZER INC. |
发明人 |
BARBER, CHRISTOPHER GORDON;BUNNAGE, MARK EDWARD;HARVEY, JOHN WILSON;MATHIAS, JOHN PAUL |
| 分类号 |
C07D409/12;A61K31/4427;A61K31/4436;A61K31/454;A61K31/517;A61K31/519;A61K31/52;A61P11/00;A61P29/00;A61P37/00;A61P37/08;C07D409/14;C07D413/14;C07D417/14;C07D471/04 |
主分类号 |
C07D409/12 |
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