METHOD FOR PREPARING ARBUTIN

摘要

FIELD: pharmaceutical industry. ^ SUBSTANCE: invention relates to a method for preparing arbutin from medicinal vegetable raw. Method for preparing arbutin involves preliminary two-fold extraction of wild strawberry leaves (Fragaria vesca L.) with 70% ethyl alcohol in water bath under the definite conditions and filtration. Then an aqueous residue obtained after evaporation is held under the definite conditions and formed precipitate of resinous substances and chlorophyll is filtered off. Filtrate (aqueous residue) is treated once with chloroform and then with ethyl acetate in water bath to remove ethyl acetate, cooled and treated three times with butanol, and arbutin is eluted from column with hot water. Arbutin-containing fractions are combined, evaporated and cooled. Proposed method provides effective enhancing the yield of the end product. ^ EFFECT: improved preparing method.