Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents

摘要

Compounds of formula (I), wherein G¹ is CH or N; G² is CH or N; R¹ is a variety of optional substituents; L¹ is (1-4C)alkylene; T¹ is CH or N; R² and R³ are independently hydrogen or (1-4C)alkyl or are joined to form a ring; X¹ and X² represent various linking groups; Ar is phenylene or certain heteroaryl rings and Q represents a variety of aromatic or heterocyclic rings systems, and pharmaceutically acceptable salts thereof are described as useful antithrombotic and anticoagulant agents, and are selective Factor Xa inhibitors. Processes for their preparation and pharmaceutical compositions containing them are also described.