| 摘要 |
A process is provided for the semi-synthesis of taxane derivatives useful in the preparation of docetaxel, in particular, the semi-synthesis of protected taxane derivatives in a one pot reaction of protecting the C-2', C-7 and C-10 and introducing a t-Boc group at the nitrogen of the amide group at the C-3' position in paclitaxel and subsequently conversion to docetaxel, and derivatives used therein.
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