发明名称 |
Process for preparing amino crotonyl compounds |
摘要 |
An improved process for preparing 4-[(3-chloro-4-fluorophenyl)amino]- 6 -{[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline and related aminocrotonyl compounds and the preparation of a suitable salt of 4-[(3-chloro-4-fluorophenyl)amino]- 6 -{[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline for use as a pharmaceutically active substance.
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申请公布号 |
US2007027170(A1) |
申请公布日期 |
2007.02.01 |
申请号 |
US20060457622 |
申请日期 |
2006.07.14 |
申请人 |
SOYKA RAINER;RALL WERNER;SCHNAUBELT JUERGEN;SIEGER PETER;KULINNA CHRISTIAN |
发明人 |
SOYKA RAINER;RALL WERNER;SCHNAUBELT JUERGEN;SIEGER PETER;KULINNA CHRISTIAN |
分类号 |
A61K31/517;A61K31/4709;A61K31/505;C07D405/02;C07D405/12 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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