摘要 |
The present invention provides novel compositions and methods for treating symptoms associated with neuropathic disorders such as hyperalgesia, allodynia, and parasthesias, using a l-aryl-3-azabicyclo[3.1.0] hexane. The invention further relates to the use of l-aryl-3-azabicyclo[3.1.0] hexanes in pharmaceutical compositions and methods for treating neuropathic disorders and related symptoms in mammals. Patients amenable to treatment according to the invention include those suffering from diabetic neuropathies, post-herpetic neuralgia, trigeminal neuralgia, chronic lower back pain, sciatica, idiopathic and post-traumatic neuropathies, HIV-associated neuropathic pain, among many other neuropathic disorders and related symptoms. |
申请人 |
DOV PHARMACEUTICAL, INC.;LIPPA, ARNOLD, S.;SKOLNICK, PHIL;BASILE, ANTHONY;CHEN, ZHENGMING;EPSTEIN, JOSEPH, W. |
发明人 |
LIPPA, ARNOLD, S.;SKOLNICK, PHIL;BASILE, ANTHONY;CHEN, ZHENGMING;EPSTEIN, JOSEPH, W. |