摘要 |
The present invention provides nucleotides, peptides, HCV mutants, and cell lines containing mutations associated with drug resistance. In addition, the present invention provides methods for screening for therapeutic compounds capable of inhibiting HCV as well as methods for inhibiting HCV, e.g., by targeting specific binding sites associated with HCV drug resistance. |
申请人 |
GILEAD SCIENCES, INC.;K.U. LEUVEN RESEARCH & DEVELOPMENT;PUERSTINGER, GERHARD;BODDEKER, NINA;NEYTS, JOHAN;SHIH, I-HUNG;VLIEGEN, INGE;ZHONG, WEIDONG |
发明人 |
BODDEKER, NINA;NEYTS, JOHAN;SHIH, I-HUNG;VLIEGEN, INGE;ZHONG, WEIDONG |