| 发明名称 |
THERAPEUTIC USE OF GROWTH FACTOR NSG33 |
| 摘要 |
<p>The present invention relates to the field of therapeutic use of proteins, genes and cells. More specifically the invention relates to therapy based on the biological function of a secreted therapeutic protein, NsG33, in particular for the treatment of disorders of the nervous system. NsG33 is a nerve survival and growth factor with antiapoptotic effects on a cell line with neuronal potential and with neuroprotective and/or neurogenesis effects on a neural precursor cell line and on primary striatal cultures. The invention also relates to novel bioactive NsG33 polypeptide fragments and the corresponding encoding DNA sequences.</p> |
| 申请公布号 |
EP1745069(A2) |
申请公布日期 |
2007.01.24 |
| 申请号 |
EP20050717160 |
申请日期 |
2005.03.30 |
| 申请人 |
NSGENE A/S |
发明人 |
GROENBORG, METTE;KUSK, PHILIP;BLOM, NIKOLAJ;PETERSEN, THOMAS;JOHANSEN, TEIT, E.;BRUNAK, SOEREN;WAHLBERG, LARS |
| 分类号 |
C07K14/475;A61K31/7088;A61K31/713;A61K38/18 |
主分类号 |
C07K14/475 |
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