发明名称 Delivery of muscle relaxants through an inhalation route
摘要 The present invention relates to the delivery of muscle relaxants through an inhalation route. Specifically, it relates to aerosols containing muscle relaxants that are used in inhalation therapy. In a method aspect of the present invention, a muscle relaxant is delivered to a patient through an inhalation route. The method comprises: a) heating a coating of a muscle relaxant, on a solid support, to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% muscle relaxant degradation products. In a kit aspect of the present invention, a kit for delivering a muscle relaxant through an inhalation route is provided which comprises: a) a coating of a muscle relaxant and b) a device for dispensing said coating a muscle relaxant as a condensation aerosol.
申请公布号 US2007014737(A1) 申请公布日期 2007.01.18
申请号 US20060523685 申请日期 2006.09.19
申请人 ALEXZA PHARMACEUTICALS, INC. 发明人 RABINOWITZ JOSHUA D.;ZAFFARONI ALEJANDRO C.
分类号 A61K9/12;A61K9/14;A61K9/00;A61K9/72;A61K31/00;A61K31/13;A61K31/137;A61K31/138;A61K31/165;A61K31/167;A61K31/19;A61K31/192;A61K31/216;A61K31/27;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/405;A61K31/407;A61K31/4196;A61K31/421;A61K31/422;A61K31/423;A61K31/437;A61K31/439;A61K31/4402;A61K31/4418;A61K31/4525;A61K31/4545;A61K31/46;A61K31/473;A61K31/48;A61K31/485;A61K31/49;A61K31/495;A61K31/496;A61K31/4985;A61K31/501;A61K31/505;A61K31/519;A61K31/53;A61K31/5415;A61K31/55;A61K31/551;A61K31/5513;A61K31/5517;A61K45/00;A61K47/48;A61L9/04;A61M11/00;A61P15/10;A61P21/02;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/32;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07D471/04;C07D487/04;F24J1/00 主分类号 A61K9/12
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