发明名称 |
Systems and methods for reverse engineering models of biological networks |
摘要 |
The present invention provides methods and accompanying computer-based systems and computer-executable code stored on a computer-readable medium for constructing a model of a biological network. The invention further provides methods for performing sensitivity analysis on a biological network and for identifying major regulators of species in the network and of the network as a whole. In addition, the invention provides methods for identifying targets of a perturbation such as that resulting from exposure to a compound or an environmental change. The invention further provides methods for identifying phenotypic mediators that contribute to differences in phenotypes of biological systems.
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申请公布号 |
US2007016390(A1) |
申请公布日期 |
2007.01.18 |
申请号 |
US20050174989 |
申请日期 |
2005.07.05 |
申请人 |
BERNARDO DIEGO D;COLLINS JAMES J;GARDNER TIMOTHY;THOMPSON MICHAEL J |
发明人 |
BERNARDO DIEGO D.;COLLINS JAMES J.;GARDNER TIMOTHY;THOMPSON MICHAEL J. |
分类号 |
G06G7/48;G06G7/58 |
主分类号 |
G06G7/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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