| 摘要 |
Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least two of the Abl, Aurora-A, Blk, c-Raf, cSRC, Src, PRK2, FGFR3, Flt3, Lck, Mekl, PDK-1, GSK3ß, EGFR, p70S6K, BMX, SGK, CaMKII, Tie-2, IGF-lR, Ron, Ret, and KDR kinases in animals, including humans, for the treatment and/or prevention of various diseases and conditions such as cancer.
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| 申请人 |
OSI PHARMACEUTICALS, INC.;AHMED, SALEH;BARBA, OSCAR;BLOXHAM, JASON;DAWSON, GRAHAM;GATTRELL, WILLIAM;KITCHIN, JOHN;PEGG, NEIL, ANTHONY;SABA, IMAAD;SADIQ, SHAZIA;SAMBROOK SMITH, COLIN, PETER;SMYTH, DON;STEINIG, ARNO, G.;WILKES, ROBIN;FOREMAN, KENNETH;WENG, QINGHUA, FELIX;STOLZ, KATHRYN;TAVARES, PAULA;PANICKER, BIJOY;LI, AN-HU;DONG, HANQING;MA, LIFU;COX, MATTHEW |
发明人 |
AHMED, SALEH;BARBA, OSCAR;BLOXHAM, JASON;DAWSON, GRAHAM;GATTRELL, WILLIAM;KITCHIN, JOHN;PEGG, NEIL, ANTHONY;SABA, IMAAD;SADIQ, SHAZIA;SAMBROOK SMITH, COLIN, PETER;SMYTH, DON;STEINIG, ARNO, G.;WILKES, ROBIN;FOREMAN, KENNETH;WENG, QINGHUA, FELIX;STOLZ, KATHRYN;TAVARES, PAULA;PANICKER, BIJOY;LI, AN-HU;DONG, HANQING;MA, LIFU;COX, MATTHEW |
