| 发明名称 |
1,1'-(1,2-ETHYNEDIYL)BIS-BENZENE DERIVATIVES AS PTP 1-B INHIBITORS |
| 摘要 |
The present invention is related to carboxylic acids of Formula (I) and use thereof for the treatment and/or prevention of obesity and/or metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin resistance, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, polycystic ovary syndrome (PCOS). In particular, the present invention is related to the use of carboxylic acids of Formula (I) to modulate, notably to inhibit the activity of PTPs. ® KIPO & WIPO 2007 |
| 申请公布号 |
KR20070008675(A) |
申请公布日期 |
2007.01.17 |
| 申请号 |
KR20067022922 |
申请日期 |
2005.03.29 |
| 申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. |
发明人 |
SWINNEN DOMINIQUE;JORAND LEBRUN CATHERINE;GERBER PATRICK;GONZALEZ JEROME;BOMBRUN AGNES |
| 分类号 |
C07C211/44;A61K31/165;C07C33/28;C07C51/31;C07C63/66;C07C65/03;C07C65/28;C07C67/343;C07C69/76;C07C211/29;C07C217/58;C07C229/38;C07C229/60;C07C229/64;C07C233/31;C07C233/65;C07C233/81;C07C233/87;C07C235/84;C07C275/24;C07C275/26;C07C275/28;C07C275/42;C07C311/04;C07C311/13;C07C311/15;C07C311/19;C07C311/21;C07C311/29;C07D319/08;C07D333/34 |
主分类号 |
C07C211/44 |
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