发明名称 |
mTOR kinase-associated proteins |
摘要 |
The invention describes isolated mTOR-associated proteins ("mTOR-APs") as well as isolated variants and fragments thereof and the isolated nucleic acids encoding them. The invention also describes vectors and host cells containing nucleic acid encoding an mTOR-AP polypeptide and methods for producing an mTOR-AP polypeptide. Also described are methods for screening for compounds which modulate mTOR-AP activity and methods for treating or preventing a disorder that is responsive to mTOR-AP modulation.
|
申请公布号 |
US2007009936(A1) |
申请公布日期 |
2007.01.11 |
申请号 |
US20060436394 |
申请日期 |
2006.05.17 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
SABATINI DAVID M.;KIM DO-HYUNG;SARBASSOV DOS D. |
分类号 |
C12Q1/68;A61K38/00;C07H21/04;C07K14/47;C07K14/705;C12P21/06 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|