发明名称 METHOD OF INHIBITING INFECTION BY HCV, OTHER FLAVIVIRIDAE VIRUSES, AND ANY OTHER VIRUS THAT COMPLEXES TO LOW DENSITY LIPOPROTEIN OR TO VERY LOW DENSITY LIPOPROTEIN IN BLOOD PREVENTING VIRAL ENTRY INTO A CELL
摘要 <p>A method of inhibiting infection by Flaviviridae viruses including HCV, GBC/HGV, and BVD in addition to VSV and any other virus capable of forming a complex with a lipoprotein strategies: preventing formation of a complex should one form, altering the conformation of such a complex to prevent its interaction with the cell receptor, blocking the cell receptor for the complex using an antibody to the receptor, blocking binding of the lipoprotein complex to the cell receptor using soluble lipoprotein receptor or fragments thereof, or downregulating the LDL receptor activity of the cells.</p>
申请公布号 EP1592445(A4) 申请公布日期 2007.01.10
申请号 EP20010989275 申请日期 2001.10.24
申请人 AGNELLO, VINCENT 发明人 AGNELLO, VINCENT
分类号 A61K45/00;A61K38/00;A61K38/17;A61K38/46;A61K39/395;A61P31/12;C07K14/705;C07K16/28;C12Q1/44;G01N33/563;G01N33/569;G01N33/92;(IPC1-7):A61K39/395;C07K1/00;C12N5/06;A61K39/42;C12Q1/70 主分类号 A61K45/00
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