Method for production of a compound in a eukaryotic cell

摘要

The present invention relates to an eukaryotic cell containing peroxisomes that are capable to fuse with a membrane-structure of the cell involved in the secretory pathway of the cell. In this way, the eukaryotic cell is able to release the peroxisomal content outside the cell. The invention also relates to a method for production of a polypeptide of interest in said eukaryotic cell wherein said polypeptide of interest is present in the peroxisome of the cell. Said polypeptide will accumulate in the peroxisome by a signal promoting peroxisome localisation. Preferred host cells are filamentous fungal cells.