| 发明名称 |
Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for beta-secretase modulation |
| 摘要 |
The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit beta-secretase (BACE) and treat beta-amyloid deposits and neurofibrillary tangles
|
| 申请公布号 |
US2007004786(A1) |
申请公布日期 |
2007.01.04 |
| 申请号 |
US20060478122 |
申请日期 |
2006.06.29 |
| 申请人 |
WYETH |
发明人 |
MALAMAS MICHAEL S.;ZHOU PING;FOBARE WILLIAM F.;SOLVIBILE WILLIAM R.;GUNAWAN IWAN S.;ERDEI JAMES J.;YAN YINFA;ANDRAE PATRICK M.;QUAGLIATO DOMINICK A. |
| 分类号 |
A61K31/427;A61K31/4196;A61K31/422;C07D403/04;C07D413/04;C07D417/04 |
主分类号 |
A61K31/427 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
