| 摘要 |
The invention relates to a novel group of phenylpiperazines having interesting pharmacological properties such as a high affinity for the dopamine D<SUB>2 </SUB>receptor and/or the serotonin reuptake site, and the ability to treat conditions related to disturbances in the dopaminergic and/or the serotonergic systems such as anxiety disorders, depression, Parkinson's disease, and schizophrenia. The invention relates to a group of novel phenylpiperazine derivatives of the formula (I): wherein: X is a group of formula 1, 2, 3, 4, 5, 6, or 7 as defined in the text, m has the value 2 to 6; n has the value 0-2; R<SUB>5 </SUB>and R<SUB>6 </SUB>are independently H or alkyl (1-3C); or R<SUB>5</SUB>+R<SUB>6 </SUB>represent a group -(CH<SUB>2</SUB>)-<SUB>p </SUB>wherein p has the value 3-5, and R<SUB>7 </SUB>is alkyl (1-3C), alkoxy (1-3C), halogen or cyano; or R<SUB>6</SUB>+R<SUB>7 </SUB>(R<SUB>7 </SUB>at position 7 of the indole group) represent a group -(CH<SUB>2</SUB>)<SUB>q </SUB>wherein q has the value 2-4, and salts thereof.
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