| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a drug substance for magnetic particle-containing medicine which can produce with good reproducibility a magnetic particle-containing medicine for diagnosis and medical treatment capable of exhibiting homogenous functional property. <P>SOLUTION: The drug substance for magnetic particle-containing medicine is a frozen body or a dried powder body consisting of a magnetic iron oxide fine particle of which the average particle size is 5-30 nm, the saturation magnetization is 35-90 Am<SP>2</SP>/kg, the coercive force is 0-6.0 kA/m and the coefficient of variation of particle size is 10% or lower; and it can be obtained by producing fine magnetic iron oxide particles, then purifying a colloidal water solution of the magnetic iron oxide fine particles by washing and removing water-soluble salts by-produced from the reaction solution at the time of reaction, with water by the usual method, and freezing it. Furthermore, a dried drug substance for the magnetic particle-containing medicine can be obtained by drying under reduced pressure. <P>COPYRIGHT: (C)2007,JPO&INPIT |
