发明名称 |
Hollow nanoparticles of protein and drug using the same |
摘要 |
The subject invention is hollow nanoparticles that comprise particle-forming first proteins (e.g. hepatitis B virus surface-antigen protein), containing a bio-recognizing molecule for recognizing a specific cell, wherein at least one of the first proteins interacts with a second protein (e.g. hepatitis B virus core-antigen protein) forming a capsid structure. With this structure, the present invention provides hollow nanoparticles, that allow transfer of a substance to a specific cell or tissue, and can be manufactured with stable productivity. The present invention further provides a drug made of the hollow nanoparticles.
|
申请公布号 |
US2006292118(A1) |
申请公布日期 |
2006.12.28 |
申请号 |
US20050529749 |
申请日期 |
2005.03.30 |
申请人 |
KURODA SHUNICHI;TANIZAWA KATSUYUKI;KONDO AKIHIKO;UEDA MASAKAZU;SENO MASAHARU |
发明人 |
KURODA SHUNICHI;TANIZAWA KATSUYUKI;KONDO AKIHIKO;UEDA MASAKAZU;SENO MASAHARU |
分类号 |
A61K48/00;C12N15/09;A61K9/16;A61K9/50;A61K9/51;A61K36/06;A61K38/00;A61K47/48;A61P31/12;A61P37/04;C07K14/02;C07K19/00;C12N1/19;C12N7/04;C12N15/88 |
主分类号 |
A61K48/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|