发明名称 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEUROPATHIC PAIN AND CLUSTER AND MIGRAINE HEADACHE- ASSOCIATED PAIN
摘要 This invention is directed to a method for preventing or treating neuropathic pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) substantially free of other enantiomers or an enantiomeric mixture wherein an enantiomer of Formula (I) predominates: wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; R1 and R2 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1- C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
申请公布号 RS4504(A) 申请公布日期 2006.12.15
申请号 YU2004P000045 申请日期 2002.07.11
申请人 ORTHO-MCNELL PHARMACEUTICAL INC. 发明人 CODD ELLEN;PLATA-SALAMAN CARLOS R.;ZHAO BOYU
分类号 A61P25/04;A61K31/27;A61K31/325;(IPC1-7):A61K31/325 主分类号 A61P25/04
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