发明名称 |
A KIT FOR MEASURING THE THROMBIN GENERATION IN A SAMPLE OF A PATIENT'S BLOOD OR PLASMA |
摘要 |
<p>The invention provides a kit for measuring the thrombin generation in a sample of a patient's blood or plasma, or in a sample of clotting factors. The kit contains lyophilized tissue factor/phospholipid-complex and a lyophilized mixture containing a thrombin-substrate and CaCl2. The invention also provides processes for preparing the reagents for the kit. The kit can be used in a method for measuring the thrombin generation in a sample, wherein it is possible to detect changes in thrombin generation kinetics, for example after administration of inhibitor bypassing agents to a patient who has developed inhibitors to an exogenous clotting factor such as Factor VIII.</p> |
申请公布号 |
EP1730299(A2) |
申请公布日期 |
2006.12.13 |
申请号 |
EP20050729048 |
申请日期 |
2005.03.30 |
申请人 |
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE SA |
发明人 |
VARADI, KATALIN;TURECEK, PETER;KEIL, BRIGITTE;PEYRER-HEIMSTAETT, SYLVIA;SCHWARZ, HANS-PETER |
分类号 |
C12Q1/56;G01N33/86 |
主分类号 |
C12Q1/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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